If player 1 has toedscruel in play with Slime Mold Colony active, is player 2 able to play Tulip? Tulip would have no viable targets as Slime Mold Colony prevents cards to hand from discard and Tulip would not be able to play to an effect.
There is a difference between no valid targets and valid targets that are blocked by an effect.
So in this case, you can play Tulip, but its effects will be blocked and Tulip will be discarded with no cards retrieved to your hand.
